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Molbank 2013, 2013(2), M800; doi:10.3390/M800
Short Note

2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide

1, 1,* , 1 and 2
1 Department of Studies in Chemistry, Mangalore University, Mangalagangotri-574 199, Karnataka, India 2 Research Department of Chemistry, P. A. College of Engineering, Nadupadavu, Mangalore 574153, Karnataka, India
* Author to whom correspondence should be addressed.
Received: 19 March 2013 / Accepted: 27 April 2013 / Published: 3 May 2013
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Abstract

S-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3H)-thione (3) by 2-chloro-N-(pyrazin-2-yl)acetamide (2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide (4). The intermediate (2), in turn, was prepared by the acetylation of 2-aminopyrazine (1) with chloroacetyl chloride. The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data.
Keywords: 1,3,4-oxadiazole; pyrazine; S-alkylation; thioether 1,3,4-oxadiazole; pyrazine; S-alkylation; thioether
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Nayak, P.S.; Narayana, B.; Samshuddin, S.; Sarojini, B.K. 2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide. Molbank 2013, 2013, M800.

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