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Molbank 2013, 2013(2), M800; doi:10.3390/M800
Short Note

2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide

1, 1,* , 1 and 2
1 Department of Studies in Chemistry, Mangalore University, Mangalagangotri-574 199, Karnataka, India 2 Research Department of Chemistry, P. A. College of Engineering, Nadupadavu, Mangalore 574153, Karnataka, India
* Author to whom correspondence should be addressed.
Received: 19 March 2013 / Accepted: 27 April 2013 / Published: 3 May 2013
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Abstract

S-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3H)-thione (3) by 2-chloro-N-(pyrazin-2-yl)acetamide (2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide (4). The intermediate (2), in turn, was prepared by the acetylation of 2-aminopyrazine (1) with chloroacetyl chloride. The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data.
Keywords: 1,3,4-oxadiazole; pyrazine; S-alkylation; thioether 1,3,4-oxadiazole; pyrazine; S-alkylation; thioether
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Nayak, P.S.; Narayana, B.; Samshuddin, S.; Sarojini, B.K. 2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide. Molbank 2013, 2013, M800.

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