Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

doi:10.3390/M787

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Molbank 2012, 2012(4), M787; doi:10.3390/M787

Short Note

Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Rita Morigi, Alessandra Locatelli, Mirella Rambaldi, Alessandro Consorti and Alberto Leoni*

Department of Pharmacy and Biotechnologies FaBiT, University of Bologna, via Belmeloro 6, 40126 Bologna, Italy

* Author to whom correspondence should be addressed.

Received: 30 October 2012 / Accepted: 15 November 2012 / Published: 20 November 2012

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Abstract: Diethyl 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine- 3,5-dicarboxylate and ethyl 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate were obtained simultaneously by the Biginelli reaction using a green protocol and curtailing reaction time.

Keywords: 3,4-dihydropyrimidin-2(1H)-ones; 1,4-dihydropyridines; imidazo[2,1-b]thiazole

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Cite This Article

MDPI and ACS Style

Morigi, R.; Locatelli, A.; Rambaldi, M.; Consorti, A.; Leoni, A. Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate. Molbank 2012, 2012, M787.

AMA Style

Morigi R, Locatelli A, Rambaldi M, Consorti A, Leoni A. Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate. Molbank. 2012; 2012(4):M787.

Chicago/Turabian Style

Morigi, Rita; Locatelli, Alessandra; Rambaldi, Mirella; Consorti, Alessandro; Leoni, Alberto. 2012. "Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate." Molbank 2012, no. 4: M787.

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