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Molbank 2012, 2012(3), M766; doi:10.3390/M766

1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one

1
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India
2
Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India
3
Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India
*
Author to whom correspondence should be addressed.
Received: 2 June 2012 / Accepted: 17 July 2012 / Published: 23 July 2012
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Abstract

The title compound, 1-(1H-benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one (2) was synthesized successfully from 4-(1H-benzimidazol-2-yl)-4-oxobutanehydrazide (1) under microwave irradiation in good yield by reacting with trichloroacetic acid, and the structure of title compound was confirmed on the basis of IR, 1H-NMR, 13C-NMR, MS and CHN analyses results.
Keywords: Benzimidazole; oxadiazole; trichloroacetic acid Benzimidazole; oxadiazole; trichloroacetic acid
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MDPI and ACS Style

Rashid, M.; Husain, A.; Mishra, R.; Ahmed, N.; Siddique, N.A. 1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one. Molbank 2012, 2012, M766.

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