1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one

doi:10.3390/M766

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Molbank 2012, 2012(3), M766; doi:10.3390/M766

Short Note

1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one

Mohd Rashid¹, Asif Husain^1,* , Ravinesh Mishra¹, Niyaz Ahmed² and Nadeem Ahmed Siddique³

¹ Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India ² Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India ³ Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India

* Author to whom correspondence should be addressed.

Received: 2 June 2012 / Accepted: 17 July 2012 / Published: 23 July 2012

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Abstract: The title compound, 1-(1H-benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one (2) was synthesized successfully from 4-(1H-benzimidazol-2-yl)-4-oxobutanehydrazide (1) under microwave irradiation in good yield by reacting with trichloroacetic acid, and the structure of title compound was confirmed on the basis of IR, ¹H-NMR, ¹³C-NMR, MS and CHN analyses results.

Keywords: Benzimidazole; oxadiazole; trichloroacetic acid

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Cite This Article

MDPI and ACS Style

Rashid, M.; Husain, A.; Mishra, R.; Ahmed, N.; Siddique, N.A. 1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one. Molbank 2012, 2012, M766.

AMA Style

Rashid M, Husain A, Mishra R, Ahmed N, Siddique NA. 1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one. Molbank. 2012; 2012(3):M766.

Chicago/Turabian Style

Rashid, Mohd; Husain, Asif; Mishra, Ravinesh; Ahmed, Niyaz; Siddique, Nadeem Ahmed. 2012. "1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one." Molbank 2012, no. 3: M766.

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