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Molbank 2009, 2009(4), M645; doi:10.3390/M645
Short Note

Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate

,  and *
Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, College of Chemistry, Shandong Normal University, Jinan 250014, China
* Author to whom correspondence should be addressed.
Received: 23 October 2009 / Accepted: 11 December 2009 / Published: 15 December 2009
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Methyl 6-methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate has been synthesized via Biginelli reaction of 4-iodobenzaldehyde, methyl acetoacetate and thiourea, promoted by microwave irradiation in the presence of iodine under solvent-free conditions in high yield and good purity.
Keywords: Biginelli reaction; solvent-free conditions; microwave irradiation; 3,4-dihydropyrimidin-2(1H)-thione Biginelli reaction; solvent-free conditions; microwave irradiation; 3,4-dihydropyrimidin-2(1H)-thione
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Pan, N.; Zhang, W.; Liu, Q. Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate. Molbank 2009, 2009, M645.

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