Next Article in Journal
Dimethyl 1,4-Dihydro-2,6-dimethyl-1-(4-methylphenyl)-4-(4-methoxylphenyl)pyridine-3,5-dicarboxylate
Previous Article in Journal
(2E)-3-(3-Methoxy-1-phenyl-1H-pyrazol-4-yl)-2-propenal
Molbank 2009, 2009(4), M645; doi:10.3390/M645
Short Note

Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate

,  and *
Received: 23 October 2009 / Accepted: 11 December 2009 / Published: 15 December 2009
Download PDF [169 KB, uploaded 15 December 2009]

Abstract

Methyl 6-methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate has been synthesized via Biginelli reaction of 4-iodobenzaldehyde, methyl acetoacetate and thiourea, promoted by microwave irradiation in the presence of iodine under solvent-free conditions in high yield and good purity.
Keywords: Biginelli reaction; solvent-free conditions; microwave irradiation; 3,4-dihydropyrimidin-2(1H)-thione Biginelli reaction; solvent-free conditions; microwave irradiation; 3,4-dihydropyrimidin-2(1H)-thione
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplements

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Pan, N.; Zhang, W.; Liu, Q. Methyl 6-Methyl-4-(4-iodophenyl)-1,2,3,4-tetrahydro-2-thioxo-5-pyrimidinecarboxylate. Molbank 2009, 2009, M645.

View more citation formats

Article Metrics

Comments

Citing Articles

[Return to top]
Molbank EISSN 1422-8599 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert