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4-Bromo-3-methoxy-1-phenyl-1H-pyrazole
Molbank 2009, 2009(4), M640; doi:10.3390/M640
Short Note

3-Chloro-4-fluoro-N-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol- 4-yl]methyl}aniline

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Received: 12 October 2009 / Accepted: 29 October 2009 / Published: 5 November 2009
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Abstract

A direct reductive amination of 3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde 2 with 3-chloro-4-flouroaniline using NaBH4/I2 as a reducing agent is described. The reaction was carried out in MeOH under neutral conditions at room temperature to give the secondary amine, 3-chloro-4-fluoro-N-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methyl}aniline (3).
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Bawa, S.; Ahmad, F.; Kumar, S. 3-Chloro-4-fluoro-N-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol- 4-yl]methyl}aniline. Molbank 2009, 2009, M640.

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