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• Thilagavathi, R
• Kavitha, HP.
• Arulmozhi, R
• Babu, S
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• Kavitha, HP.
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• Babu, S
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• Kavitha, HP.
• Arulmozhi, R
• Babu, S

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Molbank 2009, 2009(1), M589; doi:10.3390/M589

Short Note

Synthesis of 3-{4-[4-(Benzylideneamino)benzenesulfonyl]- phenyl}-2-phenylquinazolin-4(3H)-one

R. Thilagavathi ¹ , Helen P. Kavitha ¹ , R. Arulmozhi ²  and Sunil Manohar Babu ³

¹ SRM University, Ramapuram Campus, Chennai-600 089, Tamil Nadu, India ² SRM University, Kattankulathur Campus, Kanchipuram-603 203, Tamil Nadu, India ³ Nicholas Piramal Research Centre, Nicholas Piramal India Limited, Mumbai 400 063, India

* Author to whom correspondence should be addressed.

Received: 9 November 2008 / Accepted: 12 January 2009 / Published: 15 January 2009

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Abstract: The present work describes the synthesis of a Schiff base, 3-{4-[4-(benzylideneamino) benzenesulfonyl]phenyl}-2-phenylquinazolin-4(3H)-one from a novel quinazolinone, 3-[4-(4 aminobenzenesulfonyl)phenyl]-2-phenylquinazolin-4(3H)-one. The quinazolinone was prepared by reacting 2-phenyl-4H-3,1 benzoxazin-4-one with dapsone. The structure of the synthesized Schiff base is confirmed by IR, 1H NMR, 13C NMR, MS and elemental analysis.-

Keywords: 2-phenyl-4H-3; 1-benzoxazin-4-one; 3-{4-[4-(benzylideneamino)benzenesulfonyl] phenyl}-2-phenylquinazolin-4(3H)-one

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