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Int. J. Mol. Sci. 2008, 9(7), 1342-1360; doi:10.3390/ijms9071342

Third Generation Biofuels via Direct Cellulose Fermentation

1 Department of Biosystems Engineering, University of Manitoba, Winnipeg MB, Canada R3T 5V6 2 Department of Microbiology, University of Manitoba, Winnipeg MB, Canada R3T 5V6
* Author to whom correspondence should be addressed.
Received: 23 April 2008 / Revised: 11 June 2008 / Accepted: 12 June 2008 / Published: 22 July 2008
(This article belongs to the Special Issue Biofuels R&D: Securing the Planet's Future Energy Needs)
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Consolidated bioprocessing (CBP) is a system in which cellulase production, substrate hydrolysis, and fermentation are accomplished in a single process step by cellulolytic microorganisms. CBP offers the potential for lower biofuel production costs due to simpler feedstock processing, lower energy inputs, and higher conversion efficiencies than separate hydrolysis and fermentation processes, and is an economically attractive near-term goal for “third generation” biofuel production. In this review article, production of third generation biofuels from cellulosic feedstocks will be addressed in respect to the metabolism of cellulolytic bacteria and the development of strategies to increase biofuel yields through metabolic engineering.
Keywords: biofuels; ethanol; hydrogen; cellulose; fermentation. biofuels; ethanol; hydrogen; cellulose; fermentation.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Carere, C.R.; Sparling, R.; Cicek, N.; Levin, D.B. Third Generation Biofuels via Direct Cellulose Fermentation. Int. J. Mol. Sci. 2008, 9, 1342-1360.

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