Next Article in Journal
Concerted Solvent Processes for Common Sulfonyl Chloride Precursors used in the Synthesis of Sulfonamide-based Drugs
Previous Article in Journal
Remarks on Muscle Contraction Mechanism
Int. J. Mol. Sci. 2008, 9(5), 906-913; doi:10.3390/ijms9050906
Article

Headspace Solid Phase Micro Extraction Gas Chromatographic Determination of Fenthion in Human Serum

1,* , 2, 1, 2
,
3
,
4
 and
1
Received: 15 April 2008 / Revised: 22 May 2008 / Accepted: 23 May 2008 / Published: 23 May 2008
View Full-Text   |   Download PDF [191 KB, uploaded 19 June 2014]   |   Browse Figures

Abstract

A simple and effective analytical procedure was developed for the determination of fenthion residues in human serum samples. The sample treatment was performed using the headspace solid-phase micro extraction with polyacrylate fiber, which has the advantage to require low amount of serum (1 mL) without tedious pre-treatment. The quantification of fenthion was carried out by gas chromatography-mass spectrometry and the recoveries ranged from 79 to 104% at two spiking levels for 6 replicates. Detection and quantification limits were calculated as 1.51 and 4.54 ng/mL of serum respectively. Two fenthion metabolites − fenoxon and fenthion–sulfoxide − were also identified.
Keywords: Insecticide residue; olive; fenthion; headspace; SPME; GC/MS; metabolites. Insecticide residue; olive; fenthion; headspace; SPME; GC/MS; metabolites.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Kasiotis, K.M.; Souki, H.; Tsakirakis, A.N.; Carageorgiou, H.; Theotokatos, S.A.; Haroutounian, S.A.; Machera, K. Headspace Solid Phase Micro Extraction Gas Chromatographic Determination of Fenthion in Human Serum. Int. J. Mol. Sci. 2008, 9, 906-913.

View more citation formats

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert