This article is
- freely available
Interactions between Cytochrome c and DNA Strands Self-Assembled at Gold Electrode
Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China
Tianjin University of Science and Technology, Tianjin 300040, China
Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai 200030, China
* Author to whom correspondence should be addressed.
Received: 29 November 2006 / Accepted: 29 January 2007 / Published: 23 February 2007
Abstract: In this work, we reported the investigation on the interaction between DNAstrands self-assembled at gold electrodes and an electron transfer protein, cytochrome c. Weobserved that cytochrome c exhibited well-defined electrochemistry in both double-strandedand single-stranded DNA films. This suggested that the electron transfer reaction ofcytochrome c arose possibly due to the electron hopping along DNA strands rather thanwiring along the double helix. We also compared the heterogeneous electron transfer rate ofcytochrome c with that of a ruthenium complex, which further confirmed this mechanism.
Keywords: Cytochrome c; DNA; electrochemistry; gold electrodes; cyclic voltammetry
Article StatisticsClick here to load and display the download statistics.
Notes: Multiple requests from the same IP address are counted as one view.
Cite This Article
MDPI and ACS Style
Lao, R.; Wang, L.; Wan, Y.; Zhang, J.; Song, S.; Zhang, Z.; Fan, C.; He, L. Interactions between Cytochrome c and DNA Strands Self-Assembled at Gold Electrode. Int. J. Mol. Sci. 2007, 8, 136-144.
Lao R, Wang L, Wan Y, Zhang J, Song S, Zhang Z, Fan C, He L. Interactions between Cytochrome c and DNA Strands Self-Assembled at Gold Electrode. International Journal of Molecular Sciences. 2007; 8(2):136-144.
Lao, Ruojun; Wang, Lihua; Wan, Ying; Zhang, Jiong; Song, Shiping; Zhang, Zhizhou; Fan, Chunhai; He, Lin. 2007. "Interactions between Cytochrome c and DNA Strands Self-Assembled at Gold Electrode." Int. J. Mol. Sci. 8, no. 2: 136-144.