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Molecular Similarity of MDR Inhibitors
AbstractThe molecular similarity of multidrug resistance (MDR) inhibitors was evaluated using the point centred atom charge approach in an attempt to find some common features of structurally unrelated inhibitors. A series of inhibitors of bacterial MDR were studied and there is a high similarity between these in terms of their shape, presence and orientation of aromatic ring moieties. A comparison of the lipophilic properties of these molecules has also been conducted suggesting that this factor is important in MDR inhibition.
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Zloh, M.; Gibbons, S. Molecular Similarity of MDR Inhibitors. Int. J. Mol. Sci. 2004, 5, 37-47.View more citation formats
Zloh M, Gibbons S. Molecular Similarity of MDR Inhibitors. International Journal of Molecular Sciences. 2004; 5(2):37-47.Chicago/Turabian Style
Zloh, Mire; Gibbons, Simon. 2004. "Molecular Similarity of MDR Inhibitors." Int. J. Mol. Sci. 5, no. 2: 37-47.
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