Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?
Medical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences, Tehran 88777539, Iran
Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran 22439789, Iran
Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, Dushanbe 734003, Tajikistan
Nutrition and Dietetics Department, Faculty of Pharmacy, University of Concepción, Concepción, 4070386 VIII–Bio Bio Region, Chile
Institute of Pharmacology, Clinical Pharmacology and Toxicology, Medical Faculty, University of Belgrade, 11129 Belgrade, Serbia
Functional Foods, Nutraceuticals and Phytomedicine Unit, Department of Biochemistry, Federal University of Technology, Akure 340252, Nigeria
Department of Medical Parasitology, Zabol University of Medical Sciences, Zabol 61663335, Iran
Department of Biochemistry, Faculty of Science, University of Yaounde 1, Yaounde P.O. Box 812, Cameroon
Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal
Department of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, 20133 Milan, Italy
Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 11369, Iran
Department of Chemistry, Richardson College for the Environmental Science Complex, The University of Winnipeg, Winnipeg, MB R3B 2G3, Canada
Authors to whom correspondence should be addressed.
Received: 6 July 2018 / Revised: 3 August 2018 / Accepted: 7 August 2018 / Published: 10 August 2018
In this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori
infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts and isolated bioactive compounds with anti-H. pylori
activity are also critically discussed. Lastly, special attention was also given to plant extracts with urease inhibitory effects, with emphasis on involved modes of action.
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Salehi, B.; Sharopov, F.; Martorell, M.; Rajkovic, J.; Ademiluyi, A.O.; Sharifi-Rad, M.; Fokou, P.V.T.; Martins, N.; Iriti, M.; Sharifi-Rad, J. Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now? Int. J. Mol. Sci. 2018, 19, 2361.
Salehi B, Sharopov F, Martorell M, Rajkovic J, Ademiluyi AO, Sharifi-Rad M, Fokou PVT, Martins N, Iriti M, Sharifi-Rad J. Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now? International Journal of Molecular Sciences. 2018; 19(8):2361.
Salehi, Bahare; Sharopov, Farukh; Martorell, Miquel; Rajkovic, Jovana; Ademiluyi, Adedayo O.; Sharifi-Rad, Mehdi; Fokou, Patrick V.T.; Martins, Natália; Iriti, Marcello; Sharifi-Rad, Javad. 2018. "Phytochemicals in Helicobacter pylori Infections: What Are We Doing Now?" Int. J. Mol. Sci. 19, no. 8: 2361.
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