Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights
AbstractInflammation is the principal response invoked by the body to address injuries. Despite inflammation constituting a crucial component of tissue repair, it is well known that unchecked or chronic inflammation becomes deleterious, leading to progressive tissue damage. Studies over the past years focused on foods rich in polyphenols with anti-inflammatory and immunomodulatory properties, since inflammation was recognized to play a central role in several diseases. In this review, we discuss the beneficial effects of resveratrol, the most widely investigated polyphenol, on cancer and neurodegenerative, respiratory, metabolic, and cardiovascular diseases. We highlight how resveratrol, despite its unfavorable pharmacokinetics, can modulate the inflammatory pathways underlying those diseases, and we identify future opportunities for the evaluation of its clinical feasibility. View Full-Text
Share & Cite This Article
de Sá Coutinho, D.; Pacheco, M.T.; Frozza, R.L.; Bernardi, A. Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights. Int. J. Mol. Sci. 2018, 19, 1812.
de Sá Coutinho D, Pacheco MT, Frozza RL, Bernardi A. Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights. International Journal of Molecular Sciences. 2018; 19(6):1812.Chicago/Turabian Style
de Sá Coutinho, Diego; Pacheco, Maria T.; Frozza, Rudimar L.; Bernardi, Andressa. 2018. "Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights." Int. J. Mol. Sci. 19, no. 6: 1812.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.