Next Article in Journal
Live Dynamics of 53BP1 Foci Following Simultaneous Induction of Clustered and Dispersed DNA Damage in U2OS Cells
Previous Article in Journal
Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype
Article Menu
Issue 2 (February) cover image

Export Article

Open AccessOpinion
Int. J. Mol. Sci. 2018, 19(2), 518; doi:10.3390/ijms19020518

Fine-Tuning of Gene Expression by tRNA-Derived Fragments during Abiotic Stress Signal Transduction

Department of Prepharm-Med/Health Functional Biomaterials, Duksung Women’s University, Seoul 01369, Korea
*
Author to whom correspondence should be addressed.
Received: 11 January 2018 / Revised: 30 January 2018 / Accepted: 6 February 2018 / Published: 8 February 2018
(This article belongs to the Section Molecular Botany)
View Full-Text   |   Download PDF [953 KB, uploaded 8 February 2018]   |  

Abstract

When plants are subjected to unfavorable environmental conditions, overall gene expression in stressed cells is altered from a programmed pattern for normal development to an adaptive pattern for survival. Rapid changes in plant gene expression include production of stress responsive proteins for protection as well as reduction of irrelevant proteins to minimize energy consumption during growth. In addition to the many established mechanisms known to modulate gene expression in eukaryotes, a novel strategy involving tRNA-derived fragments (tRFs) was recently reported to control gene expression. In animals, tRFs are shown to play a certain role in infected or cancer cells. However, tRFs are expected to function in the regulation of gene expression against abiotic stress conditions in plants. Moreover, the underlying mechanism linking up-regulation of tRFs under stress conditions with the stress tolerant response remains unknown. In this review, the biogenesis and putative function of diverse tRFs in abiotic stress signaling are discussed with a focus on tRFs as a transcriptional/post-transcriptional/translational regulator. View Full-Text
Keywords: tRNA derived fragment; abscisic acid; abiotic stress; post-transcriptional gene silencing; plant tRNA derived fragment; abscisic acid; abiotic stress; post-transcriptional gene silencing; plant
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Park, E.J.; Kim, T.-H. Fine-Tuning of Gene Expression by tRNA-Derived Fragments during Abiotic Stress Signal Transduction. Int. J. Mol. Sci. 2018, 19, 518.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top