A Review on Ubiquitination of Neurotrophin Receptors: Facts and Perspectives
AbstractUbiquitination is a reversible post-translational modification involved in a plethora of different physiological functions. Among the substrates that are ubiquitinated, neurotrophin receptors (TrkA, TrkB, TrkC, and p75NTR) have been studied recently. TrkA is the most studied receptor in terms of its ubiquitination, and different E3 ubiquitin ligases and deubiquitinases have been implicated in its ubiquitination, whereas not much is known about the other neurotrophin receptors aside from their ubiquitination. Additional studies are needed that focus on the ubiquitination of TrkB, TrkC, and p75NTR in order to further understand the role of ubiquitination in their physiological and pathological functions. Here we review what is currently known regarding the ubiquitination of neurotrophin receptors and its physiological and pathological relevance. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Sánchez-Sánchez, J.; Arévalo, J.C. A Review on Ubiquitination of Neurotrophin Receptors: Facts and Perspectives. Int. J. Mol. Sci. 2017, 18, 630.
Sánchez-Sánchez J, Arévalo JC. A Review on Ubiquitination of Neurotrophin Receptors: Facts and Perspectives. International Journal of Molecular Sciences. 2017; 18(3):630.Chicago/Turabian Style
Sánchez-Sánchez, Julia; Arévalo, Juan C. 2017. "A Review on Ubiquitination of Neurotrophin Receptors: Facts and Perspectives." Int. J. Mol. Sci. 18, no. 3: 630.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.