Models in the Research Process of Psoriasis
AbstractPsoriasis is an ancient, universal chronic skin disease with a significant geographical variability, with the lowest incidence rate at the equator, increasing towards the poles. Insights into the mechanisms responsible for psoriasis have generated an increasing number of druggable targets and molecular drugs. The development of relevant in vitro and in vivo models of psoriasis is now a priority and an important step towards its cure. In this review, we summarize the current cellular and animal systems suited to the study of psoriasis. We discuss the strengths and limitations of the various models and the lessons learned. We conclude that, so far, there is no one model that can meet all of the research needs. Therefore, the choice model system will depend on the questions being addressed. View Full-Text
Share & Cite This Article
Bocheńska, K.; Smolińska, E.; Moskot, M.; Jakóbkiewicz-Banecka, J.; Gabig-Cimińska, M. Models in the Research Process of Psoriasis. Int. J. Mol. Sci. 2017, 18, 2514.
Bocheńska K, Smolińska E, Moskot M, Jakóbkiewicz-Banecka J, Gabig-Cimińska M. Models in the Research Process of Psoriasis. International Journal of Molecular Sciences. 2017; 18(12):2514.Chicago/Turabian Style
Bocheńska, Katarzyna; Smolińska, Elwira; Moskot, Marta; Jakóbkiewicz-Banecka, Joanna; Gabig-Cimińska, Magdalena. 2017. "Models in the Research Process of Psoriasis." Int. J. Mol. Sci. 18, no. 12: 2514.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.