The Role of miRNA in Papillary Thyroid Cancer in the Context of miRNA Let-7 Family
AbstractPapillary thyroid carcinoma (PTC) is the most common endocrine malignancy. RET/PTC rearrangement is the most common genetic modification identified in this category of cancer, increasing proliferation and dedifferentiation by the activation of the RET/PTC-RAS-BRAF-MAPK-ERK signaling pathway. Recently, let-7 miRNA was found to reduce RAS levels, acting as a tumor suppressor gene. Circulating miRNA profiles of the let-7 family may be used as novel noninvasive diagnostic, prognostic, treatment and surveillance markers for PTC. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Perdas, E.; Stawski, R.; Nowak, D.; Zubrzycka, M. The Role of miRNA in Papillary Thyroid Cancer in the Context of miRNA Let-7 Family. Int. J. Mol. Sci. 2016, 17, 909.
Perdas E, Stawski R, Nowak D, Zubrzycka M. The Role of miRNA in Papillary Thyroid Cancer in the Context of miRNA Let-7 Family. International Journal of Molecular Sciences. 2016; 17(6):909.Chicago/Turabian Style
Perdas, Ewelina; Stawski, Robert; Nowak, Dariusz; Zubrzycka, Maria. 2016. "The Role of miRNA in Papillary Thyroid Cancer in the Context of miRNA Let-7 Family." Int. J. Mol. Sci. 17, no. 6: 909.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.