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Int. J. Mol. Sci. 2016, 17(12), 1986; doi:10.3390/ijms17121986

Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin

1
Division of Molecular Systems Biology, Department of Ecogenomics and Systems Biology, Faculty of Life Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria
2
Department of Plant Biochemistry, Albrecht-von-Haller Institut, Georg-August-Universität Göttingen, Justus-von-Liebig-Weg 11, D-37077 Göttingen, Germany
*
Author to whom correspondence should be addressed.
Academic Editor: Leticia M. Estevinho
Received: 17 October 2016 / Revised: 14 November 2016 / Accepted: 21 November 2016 / Published: 26 November 2016
(This article belongs to the Special Issue Nutraceuticals in Human Health and Disease)
View Full-Text   |   Download PDF [976 KB, uploaded 26 November 2016]   |  

Abstract

The flavanol (±)-catechin shows an OH group but no 4-keto group on ring C (C3), and no conjugation between ring A and B. The related flavanone (+)-eriodictyol has a keto group on C4 but no 3-OH group on ring C. (+)-Taxifolin, another flavanone, has an OH on C3 and a keto group on C4 of the C ring. Deoxyribose degradation assay systems, with hydrogen peroxide and ascorbic acid either added or omitted, were performed in variants in which Fe(III) was added in a complex with ethylenediaminetetraacetic acid (EDTA). In combination with differential pulse voltammetry (DVP), the specific redox-chemical contributions of the ring A m-dihydroxyl groups could be explored more specifically in addition to those of the traditionally investigated o-dihydroxyl groups of ring B. View Full-Text
Keywords: flavonoids; redox chemistry; differential pulse voltammetry; deoxyribose degradation assay; Fenton reaction flavonoids; redox chemistry; differential pulse voltammetry; deoxyribose degradation assay; Fenton reaction
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Chobot, V.; Hadacek, F.; Bachmann, G.; Weckwerth, W.; Kubicova, L. Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin. Int. J. Mol. Sci. 2016, 17, 1986.

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