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Int. J. Mol. Sci. 2016, 17(10), 1667; doi:10.3390/ijms17101667

Internet-Supported Physical Exercise Training for Persons with Multiple Sclerosis—A Randomised, Controlled Study

1
Division Exercise and Health, Institute of Sport Science and Sport, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany
2
Department of Neurology, Stiftung Juliusspital, 97070 Würzburg, Germany
*
Author to whom correspondence should be addressed.
Academic Editors: Christoph Kleinschnitz and Sven Meuth
Received: 9 August 2016 / Revised: 22 September 2016 / Accepted: 26 September 2016 / Published: 30 September 2016
(This article belongs to the Special Issue Advances in Multiple Sclerosis 2016)
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Abstract

Physical exercise is effective in improving functional outcomes in persons with multiple sclerosis (pwMS). We evaluated the feasibility and effectiveness of internet-based exercise training (e-training) for pwMS on health-related quality of life (HrQoL). Secondary outcomes were muscle strength, aerobic capacity, lung function, physical activity, and fatigue. This is a randomised, controlled trial with a wait-list control group. Data were collected at baseline, after three and six months, and analysed using a hybrid linear model. One-hundred twenty-six pwMS participated in the home-based aerobic (1×/week) and strength training (2×/week) intervention that was supervised and documented via an internet-platform. The intervention group received e-training for six months, and the control group received e-training after a three months waiting period. Significant differences between the groups were only observed for muscle strength (knee flexion (effect size ES = 0.3, p = 0.003), knee extension (ES = 0.24, p = 0.015)), peak expiratory flow (ES = 0.2, p = 0.039), and sports activity (ES = 0.33, p = 0.001) after three months. E-training had no effect on HrQoL but did on muscle strength, lung function, and physical activity. It is a promising and feasible approach to facilitate large-scale, yet individual, training support. View Full-Text
Keywords: multiple sclerosis; internet; telerehabilitation; resistance training; aerobic training; exercise; physical activity; health-related quality of life; fatigue; lung function multiple sclerosis; internet; telerehabilitation; resistance training; aerobic training; exercise; physical activity; health-related quality of life; fatigue; lung function
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Tallner, A.; Streber, R.; Hentschke, C.; Morgott, M.; Geidl, W.; Mäurer, M.; Pfeifer, K. Internet-Supported Physical Exercise Training for Persons with Multiple Sclerosis—A Randomised, Controlled Study. Int. J. Mol. Sci. 2016, 17, 1667.

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