Next Article in Journal
Potential Effects of Phytoestrogen Genistein in Modulating Acute Methotrexate Chemotherapy-Induced Osteoclastogenesis and Bone Damage in Rats
Next Article in Special Issue
Characterization, Quantification, and Determination of the Toxicity of Iron Oxide Nanoparticles to the Bone Marrow Cells
Previous Article in Journal
Kynurenines and Multiple Sclerosis: The Dialogue between the Immune System and the Central Nervous System
Article Menu
Issue 8 (August) cover image

Export Article

Open AccessCommunication
Int. J. Mol. Sci. 2015, 16(8), 18283-18292; doi:10.3390/ijms160818283

Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes

1
Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia
2
Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
3
Department of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Yuping Bao
Received: 29 June 2015 / Revised: 21 July 2015 / Accepted: 29 July 2015 / Published: 6 August 2015
(This article belongs to the Special Issue Developmental and Reproductive Toxicity of Iron Oxide Nanoparticles)
View Full-Text   |   Download PDF [4027 KB, uploaded 6 August 2015]   |  

Abstract

Polydopamine-coated FeCo nanocubes (PDFCs) were successfully synthesized and tested under microwave irradiation of 2.45 GHz frequency and 0.86 W/cm2 power. These particles were found to be non-toxic in the absence of irradiation, but gained significant toxicity upon irradiation. Interestingly, no increase in relative heating rate was observed when the PDFCs were irradiated in solution, eliminating nanoparticle (NP)-induced thermal ablation as the source of toxicity. Based on these studies, we propose that microwave-induced redox processes generate the observed toxicity. View Full-Text
Keywords: FeCo nanocubes; polydopamine; microwave radiation; nanomedicine FeCo nanocubes; polydopamine; microwave radiation; nanomedicine
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Julfakyan, K.; Fatieiev, Y.; Alsaiari, S.; Deng, L.; Ezzeddine, A.; Zhang, D.; Rotello, V.M.; Khashab, N.M. Microwave-Induced Chemotoxicity of Polydopamine-Coated Magnetic Nanocubes. Int. J. Mol. Sci. 2015, 16, 18283-18292.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top