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Int. J. Mol. Sci. 2015, 16(5), 10797-10820; doi:10.3390/ijms160510797

Chemical Reactions Directed Peptide Self-Assembly

Department of Chemistry, Indian Institute of Technology Indore, Khandwa Road, Indore 452017, India
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Author to whom correspondence should be addressed.
Academic Editor: John George Hardy
Received: 20 April 2015 / Accepted: 4 May 2015 / Published: 13 May 2015
(This article belongs to the Special Issue Supramolecular Interactions)
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Abstract

Fabrication of self-assembled nanostructures is one of the important aspects in nanoscience and nanotechnology. The study of self-assembled soft materials remains an area of interest due to their potential applications in biomedicine. The versatile properties of soft materials can be tuned using a bottom up approach of small molecules. Peptide based self-assembly has significant impact in biology because of its unique features such as biocompatibility, straight peptide chain and the presence of different side chain functionality. These unique features explore peptides in various self-assembly process. In this review, we briefly introduce chemical reaction-mediated peptide self-assembly. Herein, we have emphasised enzymes, native chemical ligation and photochemical reactions in the exploration of peptide self-assembly. View Full-Text
Keywords: chemical reaction; peptide; self-assembly; enzyme; native chemical ligation chemical reaction; peptide; self-assembly; enzyme; native chemical ligation
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Rasale, D.B.; Das, A.K. Chemical Reactions Directed Peptide Self-Assembly. Int. J. Mol. Sci. 2015, 16, 10797-10820.

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