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Int. J. Mol. Sci. 2015, 16(1), 1711-1727; doi:10.3390/ijms16011711

Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore

1
Faculty of Pharmacy, Victor Babeş University of Medicine and Pharmacy, 2 Eftimie Murgu, Timisoara 300041, Romania
2
Faculty of Medicine, Victor Babeş University of Medicine and Pharmacy, 2 Eftimie Murgu, Timisoara 300041, Romania
3
Faculty of Industrial Chemistry and Environmental Engineering, Politehnica University of Timişoara, 6 Carol Telbisz, Timisoara 300001, Romania
4
Research Centre for Thermal Analysis in Environmental Problems, West University of Timişoara, Timisoara 300115, Romania
*
Author to whom correspondence should be addressed.
Academic Editor: Jurriaan Huskens
Received: 20 November 2014 / Accepted: 4 January 2015 / Published: 13 January 2015
(This article belongs to the Section Biomaterial Sciences)
View Full-Text   |   Download PDF [4888 KB, uploaded 13 January 2015]   |  

Abstract

This paper reports on the synthesis and characterization of two Schiff bases bearing 1,2,4-triazolic moieties, namely 4H-4-(2-hydroxy-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole and 4H-4-(4-nitro-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole using thin layer chromatography, melting interval, elemental analysis, spectroscopy and thermal stability studies. View Full-Text
Keywords: Schiff base; synthesis; triazole; thermal behavior; kinetic study Schiff base; synthesis; triazole; thermal behavior; kinetic study
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Ledeţi, I.; Alexa, A.; Bercean, V.; Vlase, G.; Vlase, T.; Şuta, L.-M.; Fuliaş, A. Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore. Int. J. Mol. Sci. 2015, 16, 1711-1727.

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