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Int. J. Mol. Sci. 2014, 15(8), 13424-13436; doi:10.3390/ijms150813424

The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects

1
Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan
2
Department of Biotechnology, Southern Taiwan University of Technology, Tainan 71005, Taiwan
3
Department of Biotechnology, National Formosa University, Yunlin 63201, Taiwan
4
Department of Life Sciences, National Cheng Kung University, Tainan 70101, Taiwan
5
Department of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
6
Department of Medical Laboratory Science and Biotechnology, Chung Hwa University of Medical Technology, Tainan 71703, Taiwan
7
Department of Pharmacy, National Cheng Kung University, Tainan 70101, Taiwan
8
Department of Pharmacy and Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 90741, Taiwan
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 31 May 2014 / Revised: 21 July 2014 / Accepted: 22 July 2014 / Published: 31 July 2014
(This article belongs to the Section Green Chemistry)
View Full-Text   |   Download PDF [727 KB, uploaded 31 July 2014]   |  

Abstract

Phytochemical investigation of the roots and stems of Illigera luzonensis afforded two new aporphine alkaloids (1) and (2), one new bisdehydroaporphine alkaloid (3), and one new benzenoid (4), along with 28 known structures. The structures of new compounds were elucidated by spectral and MS analysis. Among the isolated compounds, (1) and (413) were subjected into the examination for their inhibitory effects on the aggregation of washed rabbit platelets. View Full-Text
Keywords: Illigera luzonensis; aporphine; alkaloid; benzenoid; anti-platelet aggregation effect Illigera luzonensis; aporphine; alkaloid; benzenoid; anti-platelet aggregation effect
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MDPI and ACS Style

Huang, C.-H.; Chan, Y.-Y.; Kuo, P.-C.; Chen, Y.-F.; Chang, R.-J.; Chen, I.-S.; Wu, S.-J.; Wu, T.-S. The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects. Int. J. Mol. Sci. 2014, 15, 13424-13436.

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