Int. J. Mol. Sci. 2014, 15(6), 9952-9962; doi:10.3390/ijms15069952
Article

Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition

1,2,†email, 2,†email, 3email, 2email, 2email and 1,* email
Received: 25 April 2014; in revised form: 13 May 2014 / Accepted: 22 May 2014 / Published: 4 June 2014
(This article belongs to the Section Material Sciences and Nanotechnology)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Surface modification techniques have been applied to generate titanium implant surfaces that promote osseointegration for use in dental applications. In this study, strontium-doped brushite coatings were deposited on titanium by electrochemical deposition. The phase composition of the coating was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologies of the coatings were studied through scanning electron microscopy, and the cytocompatibility and bioactivity of the strontium-doped brushite coatings were evaluated using cultured osteoblasts. Osteoblast proliferation was enhanced by the addition of strontium, suggesting a possible mechanism by which strontium incorporation in brushite coatings increased bone formation surrounding the implants. Cell growth was also strongly influenced by the composition of the deposited coatings, with a 10% Sr-doped brushite coating inducing the greatest amount of bone formation among the tested materials.
Keywords: strontium; brushite; coating; implant; osteoblast; biomedical materials
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MDPI and ACS Style

Liang, Y.; Li, H.; Xu, J.; Li, X.; Qi, M.; Hu, M. Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition. Int. J. Mol. Sci. 2014, 15, 9952-9962.

AMA Style

Liang Y, Li H, Xu J, Li X, Qi M, Hu M. Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition. International Journal of Molecular Sciences. 2014; 15(6):9952-9962.

Chicago/Turabian Style

Liang, Yongqiang; Li, Haoyan; Xu, Jiang; Li, Xin; Qi, Mengchun; Hu, Min. 2014. "Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition." Int. J. Mol. Sci. 15, no. 6: 9952-9962.

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