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Int. J. Mol. Sci. 2014, 15(5), 7865-7882; doi:10.3390/ijms15057865
Review

Biomarkers in Alzheimer’s Disease Analysis by Mass Spectrometry-Based Proteomics

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 and *
Received: 19 March 2014; in revised form: 3 April 2014 / Accepted: 9 April 2014 / Published: 6 May 2014
(This article belongs to the collection Advances in Proteomic Research)
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Abstract: Alzheimer’s disease (AD) is a common chronic and destructive disease. The early diagnosis of AD is difficult, thus the need for clinically applicable biomarkers development is growing rapidly. There are many methods to biomarker discovery and identification. In this review, we aim to summarize Mass spectrometry (MS)-based proteomics studies on AD and discuss thoroughly the methods to identify candidate biomarkers in cerebrospinal fluid (CSF) and blood. This review will also discuss the potential research areas on biomarkers.
Keywords: biomarker; Alzheimer’s disease; mass spectrometry; proteomics biomarker; Alzheimer’s disease; mass spectrometry; proteomics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Liu, Y.; Qing, H.; Deng, Y. Biomarkers in Alzheimer’s Disease Analysis by Mass Spectrometry-Based Proteomics. Int. J. Mol. Sci. 2014, 15, 7865-7882.

AMA Style

Liu Y, Qing H, Deng Y. Biomarkers in Alzheimer’s Disease Analysis by Mass Spectrometry-Based Proteomics. International Journal of Molecular Sciences. 2014; 15(5):7865-7882.

Chicago/Turabian Style

Liu, Yahui; Qing, Hong; Deng, Yulin. 2014. "Biomarkers in Alzheimer’s Disease Analysis by Mass Spectrometry-Based Proteomics." Int. J. Mol. Sci. 15, no. 5: 7865-7882.


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