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Int. J. Mol. Sci. 2014, 15(5), 7750-7786; doi:10.3390/ijms15057750

Development of Drug Delivery Systems Based on Layered Hydroxides for Nanomedicine

1
Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia
2
Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia
3
Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia
*
Author to whom correspondence should be addressed.
Received: 11 February 2014 / Revised: 13 March 2014 / Accepted: 4 April 2014 / Published: 5 May 2014
(This article belongs to the Section Material Sciences and Nanotechnology)
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Abstract

Layered hydroxides (LHs) have recently fascinated researchers due to their wide application in various fields. These inorganic nanoparticles, with excellent features as nanocarriers in drug delivery systems, have the potential to play an important role in healthcare. Owing to their outstanding ion-exchange capacity, many organic pharmaceutical drugs have been intercalated into the interlayer galleries of LHs and, consequently, novel nanodrugs or smart drugs may revolutionize in the treatment of diseases. Layered hydroxides, as green nanoreservoirs with sustained drug release and cell targeting properties hold great promise of improving health and prolonging life. View Full-Text
Keywords: layered hydroxides; nanomedicine; drug delivery; nanocomposite; nanocarrier; LDH; ZLH; cytotoxicity assay layered hydroxides; nanomedicine; drug delivery; nanocomposite; nanocarrier; LDH; ZLH; cytotoxicity assay
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MDPI and ACS Style

Barahuie, F.; Hussein, M.Z.; Fakurazi, S.; Zainal, Z. Development of Drug Delivery Systems Based on Layered Hydroxides for Nanomedicine. Int. J. Mol. Sci. 2014, 15, 7750-7786.

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