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Int. J. Mol. Sci. 2014, 15(3), 3495-3506; doi:10.3390/ijms15033495
Technical Note

PseAAC-General: Fast Building Various Modes of General Form of Chou’s Pseudo-Amino Acid Composition for Large-Scale Protein Datasets

1,2,3,* , 1,2
 and 1,2
Received: 20 January 2014; in revised form: 13 February 2014 / Accepted: 14 February 2014 / Published: 26 February 2014
(This article belongs to the Special Issue Molecular Science for Drug Development and Biomedicine)
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Abstract: The general form pseudo-amino acid composition (PseAAC) has been widely used to represent protein sequences in predicting protein structural and functional attributes. We developed the program PseAAC-General to generate various different modes of Chou’s general PseAAC, such as the gene ontology mode, the functional domain mode, and the sequential evolution mode. This program allows the users to define their own desired modes. In every mode, 544 physicochemical properties of the amino acids are available for choosing. The computing efficiency is at least 100 times that of existing programs, which makes it able to facilitate the extensive studies on proteins and peptides. The PseAAC-General is freely available via SourceForge. It runs on both Linux and Windows.
Keywords: general form; large-scale datasets; pseudo-amino acid composition general form; large-scale datasets; pseudo-amino acid composition
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Du, P.; Gu, S.; Jiao, Y. PseAAC-General: Fast Building Various Modes of General Form of Chou’s Pseudo-Amino Acid Composition for Large-Scale Protein Datasets. Int. J. Mol. Sci. 2014, 15, 3495-3506.

AMA Style

Du P, Gu S, Jiao Y. PseAAC-General: Fast Building Various Modes of General Form of Chou’s Pseudo-Amino Acid Composition for Large-Scale Protein Datasets. International Journal of Molecular Sciences. 2014; 15(3):3495-3506.

Chicago/Turabian Style

Du, Pufeng; Gu, Shuwang; Jiao, Yasen. 2014. "PseAAC-General: Fast Building Various Modes of General Form of Chou’s Pseudo-Amino Acid Composition for Large-Scale Protein Datasets." Int. J. Mol. Sci. 15, no. 3: 3495-3506.


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