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Trends in Nanopharmaceutical Patents
National Institute of Industrial Property (Brazil), Mayrink Veiga, n° 9 Centro, Rio de Janeiro, Brazil
Federal University of Rio de Janeiro, Postgraduate Program on Technology of Chemical & Biochemical Processes, Av. Horácio Macedo, 2030, Centro de Tecnologia, Bloco I sala I-222, Cidade universitária, Rio de Janeiro, Brazil
Oswaldo Cruz Foundation, Institute of Scientific and Technological Communication and Information in Health, Av. Brasil, number 4.365 - Pavilhão Haity Moussatché - Manguinhos, Rio de Janeiro 21.045-360, Brazil
These authors contributed equally to this work.
* Author to whom correspondence should be addressed.
Received: 28 December 2012; in revised form: 14 March 2013 / Accepted: 15 March 2013 / Published: 27 March 2013
Abstract: Investment in nanotechnology is now a given constant by governments, research centers and companies in both more developed countries and emerging markets. Due to their characteristics, such as high stability, ability to enable antigen identification on specific cells in the human body and controlling the release of drugs and, therefore, improving therapies, nanoparticles have been the subject of research and patent applications in the pharmaceutical field. According to the Organization for Economic Co-operation and Development (OCDE), patent data can be used as a source of information in order to measure science and technology activities. Thereby, this paper presents an analysis based on patent documents related to nanotechnology in the pharmaceutical sector. As a result, the analysis of patents demonstrate primarily that nanobiotechnology attracts high levels of R&D investments, including nanoparticle-based chemotherapeutic agents/drugs, monoclonal antibody nanoparticle complexes and their role in drug delivery or contrast agents with non-toxic effects.
Keywords: health; patents; nanotechnology; pharmaceutical
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MDPI and ACS Style
Antunes, A.; Fierro, I.; Guerrante, R.; Mendes, F.; Alencar, M.S.M. Trends in Nanopharmaceutical Patents. Int. J. Mol. Sci. 2013, 14, 7016-7031.
Antunes A, Fierro I, Guerrante R, Mendes F, Alencar MSM. Trends in Nanopharmaceutical Patents. International Journal of Molecular Sciences. 2013; 14(4):7016-7031.
Antunes, Adelaide; Fierro, Iolanda; Guerrante, Rafaela; Mendes, Flavia; Alencar, Maria S.M. 2013. "Trends in Nanopharmaceutical Patents." Int. J. Mol. Sci. 14, no. 4: 7016-7031.