The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin
Abstract
:1. Introduction
2. Fallopian Tube as Extra-Ovarian Tissue of Origin of Serous Ovarian Cancer
3. Serous Tubal Intraepithelial Carcinoma (STIC) in Asymptomatic BRCA Mutation Carriers and Sporadic HGSC Cases
4. P53 Inactivation Is a Necessary but not Sufficient Step in the Etiology of HGSC
5. Modulation of DNA Repair in Carcinogenesis and Mechanisms of Chemoresistance
6. Fallopian Tube Epithelium in BRCA1/2 Mutation Carriers: Searching for the Molecular Fingerprint of Carcinogenesis
7. The Tumorigenic Effects of Oxidative Stress and Inflammation in the Fallopian Tube
8. The Molecular Basis for Malignant Transformation in Fallopian Tube Epithelium: Analysis of Cellular Pathways
9. The Genomic Sequence of Ovarian Carcinoma and Implications for Understanding the Etiology of the Cancer Cell
10. Regulation of Epithelial-Mesenchymal (EMT) Transition and Dissemination of HGSC
11. Notch Paracrine Signaling, Stemness, and Tumor Progression
12. Cancer Stem Cells in Proliferation and Survival of HGSC
13. Conclusions
Acknowledgments
Conflict of Interest
References
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Kessler, M.; Fotopoulou, C.; Meyer, T. The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin. Int. J. Mol. Sci. 2013, 14, 6571-6596. https://doi.org/10.3390/ijms14046571
Kessler M, Fotopoulou C, Meyer T. The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin. International Journal of Molecular Sciences. 2013; 14(4):6571-6596. https://doi.org/10.3390/ijms14046571
Chicago/Turabian StyleKessler, Mirjana, Christina Fotopoulou, and Thomas Meyer. 2013. "The Molecular Fingerprint of High Grade Serous Ovarian Cancer Reflects Its Fallopian Tube Origin" International Journal of Molecular Sciences 14, no. 4: 6571-6596. https://doi.org/10.3390/ijms14046571