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Int. J. Mol. Sci. 2013, 14(3), 5775-5783; doi:10.3390/ijms14035775
Communication

Exploiting BSA to Inhibit the Fibrous Aggregation of Magnetic Nanoparticles under an Alternating Magnetic Field

1
,
2
,
1
,
1
 and
1,*
1 State Key Laboratory of Bioelectronics and Jiangsu Key Laboratory of Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Dingjiaqiao 87, Nanjing 210009, China 2 School of Medicine, Southeast University, Dingjiaqiao 87, Nanjing 210009, China
* Author to whom correspondence should be addressed.
Received: 26 November 2012 / Revised: 6 February 2013 / Accepted: 15 February 2013 / Published: 12 March 2013
(This article belongs to the Special Issue Molecular Self-Assembly 2012)
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Abstract

The alternating magnetic field was discovered to be capable of inducing the fibrous aggregation of magnetic nanoparticles. However, this anisotropic aggregation may be unfavorable for practical applications. Here, we reported that the adsorption of BSA (bovine serum albumin) on the surfaces of magnetic nanoparticles can effectively make the fibrous aggregation of γ-Fe2O3 nanoparticles turn into a more isotropic aggregation in the presence of the alternating magnetic field. Also, the heating curves with and without BSA adsorption under different pH conditions were measured to show the influence of the colloidal aggregation states on the collective calorific behavior of magnetic nanoparticles.
Keywords: alternating magnetic field; colloidal assembly; biomolecule; bioelectronics alternating magnetic field; colloidal assembly; biomolecule; bioelectronics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sun, J.F.; Liu, X.; Chen, Y.; Zhang, Y.; Gu, N. Exploiting BSA to Inhibit the Fibrous Aggregation of Magnetic Nanoparticles under an Alternating Magnetic Field. Int. J. Mol. Sci. 2013, 14, 5775-5783.

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