Int. J. Mol. Sci. 2013, 14(3), 5775-5783; doi:10.3390/ijms14035775
Communication

Exploiting BSA to Inhibit the Fibrous Aggregation of Magnetic Nanoparticles under an Alternating Magnetic Field

Jian Fei Sun 1 email, Xuan Liu 2 email, Yuan Chen 1 email, Yu Zhang 1 email and Ning Gu 1,* email
1 State Key Laboratory of Bioelectronics and Jiangsu Key Laboratory of Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Dingjiaqiao 87, Nanjing 210009, China 2 School of Medicine, Southeast University, Dingjiaqiao 87, Nanjing 210009, China
* Author to whom correspondence should be addressed.
Received: 26 November 2012; in revised form: 6 February 2013 / Accepted: 15 February 2013 / Published: 12 March 2013
(This article belongs to the Special Issue Molecular Self-Assembly 2012)
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Abstract: The alternating magnetic field was discovered to be capable of inducing the fibrous aggregation of magnetic nanoparticles. However, this anisotropic aggregation may be unfavorable for practical applications. Here, we reported that the adsorption of BSA (bovine serum albumin) on the surfaces of magnetic nanoparticles can effectively make the fibrous aggregation of γ-Fe2O3 nanoparticles turn into a more isotropic aggregation in the presence of the alternating magnetic field. Also, the heating curves with and without BSA adsorption under different pH conditions were measured to show the influence of the colloidal aggregation states on the collective calorific behavior of magnetic nanoparticles.
Keywords: alternating magnetic field; colloidal assembly; biomolecule; bioelectronics

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Cite This Article

MDPI and ACS Style

Sun, J.F.; Liu, X.; Chen, Y.; Zhang, Y.; Gu, N. Exploiting BSA to Inhibit the Fibrous Aggregation of Magnetic Nanoparticles under an Alternating Magnetic Field. Int. J. Mol. Sci. 2013, 14, 5775-5783.

AMA Style

Sun JF, Liu X, Chen Y, Zhang Y, Gu N. Exploiting BSA to Inhibit the Fibrous Aggregation of Magnetic Nanoparticles under an Alternating Magnetic Field. International Journal of Molecular Sciences. 2013; 14(3):5775-5783.

Chicago/Turabian Style

Sun, Jian F.; Liu, Xuan; Chen, Yuan; Zhang, Yu; Gu, Ning. 2013. "Exploiting BSA to Inhibit the Fibrous Aggregation of Magnetic Nanoparticles under an Alternating Magnetic Field." Int. J. Mol. Sci. 14, no. 3: 5775-5783.

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