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Int. J. Mol. Sci. 2012, 13(4), 5035-5047; doi:10.3390/ijms13045035
Article

A Novel and Expedient Approach to New Thiazoles, Thiazolo[3,2-a]pyridines, Dihydrothiophenes, and Hydrazones Incorporating Thieno[2,3-b]thiophene Moiety

1,* , 1,* , 1
, 1
 and 2
Received: 1 March 2012; in revised form: 31 March 2012 / Accepted: 12 April 2012 / Published: 23 April 2012
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Abstract: This paper reports details about the synthesis of a series of novel functionalized symmetrical bis-heterocyclic compounds containing a thieno[2,3-b]thiophene motif. Bis-thiazole derivatives 2, 3a-c and thiazolo[3,2-a]pyridine derivatives 4a-c are achieved. The hitherto unknown dihydrothiophene derivatives 6a-d via bis-pyridimium salt 5 are obtained. Additionally, the novel hydrazonothieno[2,3-b]thiophene derivatives 10a-c are obtained via bis-tosylacetylthieno[2,3-b]thiophene derivative 9. All compounds are characterized by 1H-, 13C-NMR, GCMS, IR, and UV-vis spectrometry. These compounds represent a new class of sulfur and nitrogen containing heterocycles that should also be of interest as new materials.
Keywords: thiazolo[3,2-a]pyridine; dihydrothiphene; thieno[2,3-b]thiophene; symmetrical bis-heterocycle thiazolo[3,2-a]pyridine; dihydrothiphene; thieno[2,3-b]thiophene; symmetrical bis-heterocycle
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Mabkhot, Y.N.; Barakat, A.; Al-Majid, A.M.; Alamary, A.S.; Al-Nahary, T.T. A Novel and Expedient Approach to New Thiazoles, Thiazolo[3,2-a]pyridines, Dihydrothiophenes, and Hydrazones Incorporating Thieno[2,3-b]thiophene Moiety. Int. J. Mol. Sci. 2012, 13, 5035-5047.

AMA Style

Mabkhot YN, Barakat A, Al-Majid AM, Alamary AS, Al-Nahary TT. A Novel and Expedient Approach to New Thiazoles, Thiazolo[3,2-a]pyridines, Dihydrothiophenes, and Hydrazones Incorporating Thieno[2,3-b]thiophene Moiety. International Journal of Molecular Sciences. 2012; 13(4):5035-5047.

Chicago/Turabian Style

Mabkhot, Yahia Nasser; Barakat, Assem; Al-Majid, Abdullah Mohammad; Alamary, Abdullah Saleh; Al-Nahary, Taleb T. 2012. "A Novel and Expedient Approach to New Thiazoles, Thiazolo[3,2-a]pyridines, Dihydrothiophenes, and Hydrazones Incorporating Thieno[2,3-b]thiophene Moiety." Int. J. Mol. Sci. 13, no. 4: 5035-5047.


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