Next Article in Journal
Previous Article in Journal
Int. J. Mol. Sci. 2012, 13(11), 15241-15251; doi:10.3390/ijms131115241
Article

Synthesis Method for Thiosulfonate and Report of Its Insecticidal Activity in Anagasta kuehniella (Lepidoptera: Pyralidae)

1
, 2
, 1
, 2
, 1
 and 2,*
Received: 12 July 2012; in revised form: 6 November 2012 / Accepted: 10 November 2012 / Published: 19 November 2012
View Full-Text   |   Download PDF [227 KB, updated 19 June 2014; original version uploaded 19 June 2014]   |   Browse Figures
Abstract: Insect pests have caused economic losses valued at billions of dollars in agricultural production. Anagasta kuehniella (Zeller), the Mediterranean flour moth, is of major economic importance as a flour and grain feeder and is often a severe pest in flourmills. This study provides a suitable route for the direct preparation of thiosulfonates 2 and 3 from thiols, under mild conditions, with good yields; these thiosulfonates were tested for their regulatory effect on insect growth. The chronic ingestion of thiosulfonates resulted in a significant reduction in larval survival and weight. In addition, the tryptic activity of larvae was sensitive to these thiosulfonates. Results suggest that thiosulfonates 2 and 3 have a potential antimetabolic effect when ingested by A. kuehniella. The use of AgNO3/BF3·OEt2 and Al(H2PO4)3/HNO3 provides a suitable route for the direct preparation of thiosulfonates from thiols under mild conditions with good yields. These thiosulfonates were toxic for A. kuehniella larvae, suggesting their potential as biotechnological tools.
Keywords: insect pests; insecticidal activity; growth retardation; thiosulfonates insect pests; insecticidal activity; growth retardation; thiosulfonates
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

dos Santos, E.A.; Gonçalves, F.M.; Prado, P.C.; Sasaki, D.Y.; de Lima, D.P.; Macedo, M.L.R. Synthesis Method for Thiosulfonate and Report of Its Insecticidal Activity in Anagasta kuehniella (Lepidoptera: Pyralidae). Int. J. Mol. Sci. 2012, 13, 15241-15251.

AMA Style

dos Santos EA, Gonçalves FM, Prado PC, Sasaki DY, de Lima DP, Macedo MLR. Synthesis Method for Thiosulfonate and Report of Its Insecticidal Activity in Anagasta kuehniella (Lepidoptera: Pyralidae). International Journal of Molecular Sciences. 2012; 13(11):15241-15251.

Chicago/Turabian Style

dos Santos, Edson A.; Gonçalves, Fernando M.; Prado, Paulo C.; Sasaki, Daniele Y.; de Lima, Dênis P.; Macedo, Maria L.R. 2012. "Synthesis Method for Thiosulfonate and Report of Its Insecticidal Activity in Anagasta kuehniella (Lepidoptera: Pyralidae)." Int. J. Mol. Sci. 13, no. 11: 15241-15251.



Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert