Int. J. Mol. Sci. 2012, 13(1), 1006-1017; doi:10.3390/ijms13011006
Article

Photostability of Isovaline and its Precursor 5-Ethyl-5-methylhydantoin Exposed to Simulated Space Radiations

Palash K. Sarker 1,* email, Jun-ichi Takahashi 2 email, Yukinori Kawamoto 1 email, Yumiko Obayashi 1 email, Takeo Kaneko 1 email and Kensei Kobayashi 1 email
1 Department of Chemistry and Biotechnology, Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama 240-8501, Japan 2 NTT Microsystem Integration Laboratories, 3-1 Morinosato Wakamiya, Atsugi 243-0198, Japan
* Author to whom correspondence should be addressed.
Received: 9 November 2011; in revised form: 4 January 2012 / Accepted: 9 January 2012 / Published: 17 January 2012
(This article belongs to the Section Physical Chemistry, Theoretical and Computational Chemistry)
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Abstract: Aqueous solutions of isovaline and its precursor molecule, 5-ethyl-5-methylhydantoin, were irradiated with ultraviolet and γ-ray photons, to evaluate their structural stability against space radiation. The degree of photolysis was measured and irradiation products were identified using chiral, reversed-phase and ion-exchange high-performance liquid chromatography. The experimental results show that the degree of photolysis of 5-ethyl-5-methylhydantoin is more significant than that of isovaline under ultraviolet light irradiation, while the results under γ-ray irradiation are the opposite. As the products of isovaline photolysis, aspartic acid, serine, glutamic acid and alanine were dominantly detected.
Keywords: isovaline; space radiation; ultraviolet light; gamma ray; photolysis

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Cite This Article

MDPI and ACS Style

Sarker, P.K.; Takahashi, J.-I.; Kawamoto, Y.; Obayashi, Y.; Kaneko, T.; Kobayashi, K. Photostability of Isovaline and its Precursor 5-Ethyl-5-methylhydantoin Exposed to Simulated Space Radiations. Int. J. Mol. Sci. 2012, 13, 1006-1017.

AMA Style

Sarker PK, Takahashi J-I, Kawamoto Y, Obayashi Y, Kaneko T, Kobayashi K. Photostability of Isovaline and its Precursor 5-Ethyl-5-methylhydantoin Exposed to Simulated Space Radiations. International Journal of Molecular Sciences. 2012; 13(1):1006-1017.

Chicago/Turabian Style

Sarker, Palash K.; Takahashi, Jun-ichi; Kawamoto, Yukinori; Obayashi, Yumiko; Kaneko, Takeo; Kobayashi, Kensei. 2012. "Photostability of Isovaline and its Precursor 5-Ethyl-5-methylhydantoin Exposed to Simulated Space Radiations." Int. J. Mol. Sci. 13, no. 1: 1006-1017.

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