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Int. J. Mol. Sci. 2011, 12(8), 4946-4952; doi:10.3390/ijms12084946

A New Benzofuran Glucoside from Ficus Tikoua Bur

Received: 11 July 2011 / Revised: 22 July 2011 / Accepted: 26 July 2011 / Published: 3 August 2011
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
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From the water-soluble portion of the methanol extract of stems of Ficus tikoua Bur., a new benzofuran glucoside, named 6-carboxyethyl-5-hydroxybenzofuran 5-O-β-D-glucopyranoside (1), together with one known benzofuran glucoside (2) were isolated. Their structures were elucidated by 1D and 2D (1H-1H COSY, HMQC, and HMBC) NMR spectroscopy and HRMS techniques. The antioxidant activities of the isolated compounds were assayed based on the scavenging activities of DPPH free radical. Compounds 1 and 2 exhibited moderate antioxidant activities, and the IC50 values were 242.8 μg·mL1 and 324.9 μg·mL−1, respectively.
Keywords: Ficus tikoua Bur.; benzofuran glucoside; antioxidant activity Ficus tikoua Bur.; benzofuran glucoside; antioxidant activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wei, S.-P.; Luan, J.-Y.; Lu, L.-N.; Wu, W.-J.; Ji, Z.-Q. A New Benzofuran Glucoside from Ficus Tikoua Bur. Int. J. Mol. Sci. 2011, 12, 4946-4952.

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