Int. J. Mol. Sci. 2011, 12(5), 3085-3101; doi:10.3390/ijms12053085
Article

Required Levels of Catalysis for Emergence of Autocatalytic Sets in Models of Chemical Reaction Systems

1 Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland 2 Tampere University of Technology, Finland 3 University of Vermont, 85 South Prospect Street Burlington, VT 05405, USA 4 Santa Fe Institute, 1399 Hyde Park Road Santa Fe, NM 87501, USA 5 Department of Mathematics and Statistics, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
* Author to whom correspondence should be addressed.
Received: 18 February 2011; in revised form: 18 April 2011 / Accepted: 5 May 2011 / Published: 12 May 2011
(This article belongs to the Special Issue Origin of Life 2011)
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Abstract: The formation of a self-sustaining autocatalytic chemical network is a necessary but not sufficient condition for the origin of life. The question of whether such a network could form “by chance” within a sufficiently complex suite of molecules and reactions is one that we have investigated for a simple chemical reaction model based on polymer ligation and cleavage. In this paper, we extend this work in several further directions. In particular, we investigate in more detail the levels of catalysis required for a self-sustaining autocatalytic network to form. We study the size of chemical networks within which we might expect to find such an autocatalytic subset, and we extend the theoretical and computational analyses to models in which catalysis requires template matching.
Keywords: autocatalytic sets; chemical reaction networks; template-based catalysis; origin of life

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MDPI and ACS Style

Hordijk, W.; Kauffman, S.A.; Steel, M. Required Levels of Catalysis for Emergence of Autocatalytic Sets in Models of Chemical Reaction Systems. Int. J. Mol. Sci. 2011, 12, 3085-3101.

AMA Style

Hordijk W, Kauffman SA, Steel M. Required Levels of Catalysis for Emergence of Autocatalytic Sets in Models of Chemical Reaction Systems. International Journal of Molecular Sciences. 2011; 12(5):3085-3101.

Chicago/Turabian Style

Hordijk, Wim; Kauffman, Stuart A.; Steel, Mike. 2011. "Required Levels of Catalysis for Emergence of Autocatalytic Sets in Models of Chemical Reaction Systems." Int. J. Mol. Sci. 12, no. 5: 3085-3101.

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