Melanogenesis Inhibitory Activity of Two Generic Drugs: Cinnarizine and Trazodone in Mouse B16 Melanoma Cells
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental Section
3.1. Materials
3.2. Cell Cultures and Drug Treatments
3.3. Measurements of Cell Viability
3.4. Fontana-Masson Stain
3.5. Determination of Melanin Content
3.6. Measurements of Tyrosinase Activity
3.7. Statistical Analysis
4. Conclusions
Acknowledgments
- Conflict of InterestThe author declares no conflict of interest.
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The generic drugs screened in this study | ||||
---|---|---|---|---|
Acarbose | Colchicine | Fexofenadine | Meloxicam | Pertiazem |
Acemetacin | Cortisone | Fluconazole | Mepenzolate | Phenytoin |
Acetaminophen | Coumadin | Fludiazepam | Mephenoxalone | Pioglitazone |
Aldioxa | Cyprohetadine | Flunarizine | Mequitazine | Piracetam |
Allopurinol | Dacoton | Fluoxetine | Metformin | Polaramine |
Alusa | Danazol | Formoterol | Methimazole | Ranitidine |
Ambroxol | Dexamethasone | Furosemide | Methocarbamol | Rifater |
Amlodipine | Dexchlorpheniramine | Gemfibrozil | Methotrexate | Ritampin |
Amoxicillin | Diclofenac potassium | Ginkgoflavon | Metoclopramide | Rosiglitazone |
Apresoline | Dicloxacillin | Glibenclamide | Metronidazole | Selegiline |
Aspirin | Dihydroergotoxine | Glimepiride | Mexiletine | Sennoside |
Atenolol | Dimethicone | Glipizide | Miconazole | Silymarin |
Baclofen | Diovan | Glucosamine | Minocycline | Simvastatin |
Benzbromarone | Diphenidol | Homochlorcyclizine | Mosapride | Songora |
Benzonatate | Dipyridamole | Hydralazine | Nalidixic acid | Souriree |
Bethanechol | Ditiazem | Hydroxychloroquine | Naproxen | Spironolaotone |
Biorix | Domperidol | Hydroxyzine | Narcaricin | Strocain |
Bisacodyl | Doxazosin | Hyoscyamine | Neomycin | Sulfinpyrazone |
Bismuth | Doxycycline | Ibuprofen | Nicardipine | Sulindac |
Bisoprolol | Doxymycin | Imdur | Nicergoline | Tamoxifen |
Bromhexine | Elistin | Indapamide | Nicorandil | Terazosin |
Captopril | Enalapril | Indomethanoin | Nifedipine | Theophyllin |
Carvedilol | Entacapone | Iodopropylidene | Nifuroxazide | Thyroxine |
Cefadroxil | Enzdase | Isoniazid | Nimodipine | Trazodone |
Celecoxib | Eprazine | Isosorbide | Nitroxoline | Trihexyphenidy |
Cephalexin | Ergonovine | Ketoconazole | Nystatin | Trimethoprim |
Cetirizine | Erythromycin | Ketorolac | Ofloxacin | Tsurupinate |
Cimetidine | Escitalopram | Levamisole | Oxatomide | Uliden |
Cinnarizine | Ethambutol | Loperamide | Pantoprazole | Ultracet |
Ciprofloxacin | Famotidine | Loratadine | Pecolin | Valproic acid |
Clindamycin | Felodipine | Mapirocin | Pentoxifylline | Verapamil |
Clonazepam | Fenoterol | Mebendazole | Peptidin | Warfarin |
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Share and Cite
Chang, T.-S.; Lin, V.C.-H. Melanogenesis Inhibitory Activity of Two Generic Drugs: Cinnarizine and Trazodone in Mouse B16 Melanoma Cells. Int. J. Mol. Sci. 2011, 12, 8787-8796. https://doi.org/10.3390/ijms12128787
Chang T-S, Lin VC-H. Melanogenesis Inhibitory Activity of Two Generic Drugs: Cinnarizine and Trazodone in Mouse B16 Melanoma Cells. International Journal of Molecular Sciences. 2011; 12(12):8787-8796. https://doi.org/10.3390/ijms12128787
Chicago/Turabian StyleChang, Te-Sheng, and Victor Chia-Hsiang Lin. 2011. "Melanogenesis Inhibitory Activity of Two Generic Drugs: Cinnarizine and Trazodone in Mouse B16 Melanoma Cells" International Journal of Molecular Sciences 12, no. 12: 8787-8796. https://doi.org/10.3390/ijms12128787