Abstract: Chemical composition, antioxidant and antimicrobial activities of the fresh leaves and stems oils of Piper caninum were investigated. A total of forty eight constituents were identified in the leaves (77.9%) and stems (87.0%) oil which were characterized by high proportions of phenylpropanoid, safrole with 17.1% for leaves and 25.5% for stems oil. Antioxidant activities were evaluated by using β-carotene/linoleic acid bleaching, DPPH radical scavenging and total phenolic content. Stems oil showed the highest inhibitory activity towards lipid peroxidation (114.9 ± 0.9%), compared to BHT (95.5 ± 0.5%), while leaves oil showed significant total phenolic content (27.4 ± 0.5 mg GA/g) equivalent to gallic acid. However, the essential oils showed weak activity towards DPPH free-radical scavenging. Evaluation of antimicrobial activity revealed that both oils exhibited strong activity against all bacteria strains with MIC values in the range 62.5 to 250 µg/mL, but weak activity against fungal strains. These findings suggest that the essential oils can be used as antioxidant and antimicrobial agents for therapeutic, nutraceutical industries and food manufactures.
Keywords: essential oil; Piperaceae; Piper caninum; antioxidant; antimicrobial
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Salleh, W.M.N.H.W.; Ahmad, F.; Yen, K.H.; Sirat, H.M. Chemical Compositions, Antioxidant and Antimicrobial Activities of Essential Oils of Piper caninum Blume. Int. J. Mol. Sci. 2011, 12, 7720-7731.
Salleh WMNHW, Ahmad F, Yen KH, Sirat HM. Chemical Compositions, Antioxidant and Antimicrobial Activities of Essential Oils of Piper caninum Blume. International Journal of Molecular Sciences. 2011; 12(11):7720-7731.
Salleh, Wan Mohd Nuzul Hakimi Wan; Ahmad, Farediah; Yen, Khong Heng; Sirat, Hasnah Mohd. 2011. "Chemical Compositions, Antioxidant and Antimicrobial Activities of Essential Oils of Piper caninum Blume." Int. J. Mol. Sci. 12, no. 11: 7720-7731.