Int. J. Mol. Sci. 2010, 11(2), 521-531; doi:10.3390/ijms11020521
Article

Nuclear Translocation of Nuclear Factor Kappa B in First Trimester Deciduas and Chorionic Villi in Early Spontaneous Miscarriage Women

1email, 2,* email, 3email and 1email
Received: 24 December 2009; in revised form: 20 January 2010 / Accepted: 21 January 2010 / Published: 3 February 2010
(This article belongs to the Section Biochemistry, Molecular Biology and Biophysics)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The nuclear factor kappa B is widely expressed in the distinct subpopulations of chorionic villi and deciduas of first-trimester pregnancies. We examined the cellular distribution and expression of nuclear factor kappa B in the human first-trimester chorionic villi and deciduas of women with early spontaneous miscarriage and viable pregnancy by confocal laser scanning microscope and immunohistochemistry. There is a greater nuclear translocation of nuclear factor kappa B is restricted to villous stromal cells, decidual stromal cells, glandular epithelial cells and vessel endothelial cells in early spontaneous miscarriage than in viable pregnancies. Collectively these observations suggest that over-activation of nuclear factor kappa B has a relationship with early spontaneous miscarriages.
Keywords: early spontaneous miscarriage; nuclear factor kappa B; confocal laser scanning microscope; immunohistochemistry
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MDPI and ACS Style

Wang, L.-Q.; Yu, X.-W.; Yan, C.-F.; Wang, X. Nuclear Translocation of Nuclear Factor Kappa B in First Trimester Deciduas and Chorionic Villi in Early Spontaneous Miscarriage Women. Int. J. Mol. Sci. 2010, 11, 521-531.

AMA Style

Wang L-Q, Yu X-W, Yan C-F, Wang X. Nuclear Translocation of Nuclear Factor Kappa B in First Trimester Deciduas and Chorionic Villi in Early Spontaneous Miscarriage Women. International Journal of Molecular Sciences. 2010; 11(2):521-531.

Chicago/Turabian Style

Wang, Li-qin; Yu, Xue-wen; Yan, Chun-fang; Wang, Xiang. 2010. "Nuclear Translocation of Nuclear Factor Kappa B in First Trimester Deciduas and Chorionic Villi in Early Spontaneous Miscarriage Women." Int. J. Mol. Sci. 11, no. 2: 521-531.

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