Int. J. Mol. Sci. 2010, 11(1), 354-369; doi:10.3390/ijms11010354
Review

Surface Modification of Biomedical and Dental Implants and the Processes of Inflammation, Wound Healing and Bone Formation

Clark M. Stanfordemail
Dows Institute for Dental Research, College of Dentistry, University of Iowa, IA 52242, USA
Received: 24 December 2009; in revised form: 18 January 2010 / Accepted: 20 January 2010 / Published: 25 January 2010
(This article belongs to the Special Issue Dental Materials)
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Abstract: Bone adaptation or integration of an implant is characterized by a series of biological reactions that start with bone turnover at the interface (a process of localized necrosis), followed by rapid repair. The wound healing response is guided by a complex activation of macrophages leading to tissue turnover and new osteoblast differentiation on the implant surface. The complex role of implant surface topography and impact on healing response plays a role in biological criteria that can guide the design and development of future tissue-implant surface interfaces.
Keywords: implant; surfaces; wound healing; macrophage

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MDPI and ACS Style

Stanford, C.M. Surface Modification of Biomedical and Dental Implants and the Processes of Inflammation, Wound Healing and Bone Formation. Int. J. Mol. Sci. 2010, 11, 354-369.

AMA Style

Stanford CM. Surface Modification of Biomedical and Dental Implants and the Processes of Inflammation, Wound Healing and Bone Formation. International Journal of Molecular Sciences. 2010; 11(1):354-369.

Chicago/Turabian Style

Stanford, Clark M. 2010. "Surface Modification of Biomedical and Dental Implants and the Processes of Inflammation, Wound Healing and Bone Formation." Int. J. Mol. Sci. 11, no. 1: 354-369.

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