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Int. J. Mol. Sci. 2009, 10(5), 1942-1949; doi:10.3390/ijms10051942

Glycosylation of Fluorophenols by Plant Cell Cultures

1,* , 1, 2, 2 and 1,*
1 Department of Chemistry, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan 2 Department of Life Science, Okayama University of Science, 1-1 Ridai-cho, Okayama 700-0005, Japan
* Authors to whom correspondence should be addressed.
Received: 10 February 2009 / Revised: 10 April 2009 / Accepted: 24 April 2009 / Published: 27 April 2009
(This article belongs to the Special Issue Biodegradability of Materials)
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Fluoroaromatic compounds are used as agrochemicals and released into environment as pollutants. Glycosylation of 2-, 3-, and 4-fluorophenols using plant cell cultures of Nicotiana tabacum was investigated to elucidate their potential to metabolize these compounds. Cultured N. tabacum cells converted 2-fluorophenol into its β-glucoside (60%) and β-gentiobioside (10%). 4-Fluorophenol was also glycosylated to its β-glucoside (32%) and β-gentiobioside (6%) by N. tabacum cells. On the other hand, N. tabacum glycosylated 3-fluorophenol to β-glucoside (17%).
Keywords: Fluorophenol; Glycosylation; Nicotiana Tabacum; Plant Cell Cultures Fluorophenol; Glycosylation; Nicotiana Tabacum; Plant Cell Cultures
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Shimoda, K.; Kubota, N.; Kondo, Y.; Sato, D.; Hamada, H. Glycosylation of Fluorophenols by Plant Cell Cultures. Int. J. Mol. Sci. 2009, 10, 1942-1949.

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