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Molecules 2003, 8(7), 536-540; doi:10.3390/80700536

Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives

 and *
Department of Organic Chemistry, Slovak University of Technology, Radlinského Street 9, Slovakia
* Author to whom correspondence should be addressed.
Received: 13 June 2003 / Accepted: 26 June 2003 / Published: 15 July 2003
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We present 1-pentafluorophenyl-1H-pyrrole and some of its electrophilic substitution reactions: formylation and acetylations. The 2-substituted products formed in these reactions are selectively and in high yield converted into 3-substituted products by treatment with trifluoromethanesulfonic acid. A general synthesis of 3-acylpyrroles was developed by the trifluoromethanesulfonic acid-mediated rearrangement of the corresponding 2-acylpyrroles.
Keywords: Conducting materials; supramolecular synthons; pyrroles Conducting materials; supramolecular synthons; pyrroles
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Hrnčariková, K.; Végh, D. Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives. Molecules 2003, 8, 536-540.

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