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Molecules 2003, 8(11), 793-865; doi:10.3390/81100793
Review

The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

1,* , 1 and 2
1 Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt 2 National Organization for Drug Control and Research (NODCAR), P.O. Box 29, Cairo, Egypt
* Author to whom correspondence should be addressed.
Received: 21 June 2003 / Revised: 15 August 2003 / Accepted: 18 August 2003 / Published: 15 November 2003

Abstract

The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alkynes are discussed.
Keywords: α-Haloketones; annelated heterocycles; oxygen nucleophiles; nitrogen nucleophiles; sulfur nucleophiles; carbon nucleophiles α-Haloketones; annelated heterocycles; oxygen nucleophiles; nitrogen nucleophiles; sulfur nucleophiles; carbon nucleophiles
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Erian, A.W.; Sherif, S.M.; Gaber, H.M. The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis. Molecules 2003, 8, 793-865.

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