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Molecules 2003, 8(11), 793-865; doi:10.3390/81100793

The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

1
Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt
2
National Organization for Drug Control and Research (NODCAR), P.O. Box 29, Cairo, Egypt
*
Author to whom correspondence should be addressed.
Received: 21 June 2003 / Revised: 15 August 2003 / Accepted: 18 August 2003 / Published: 15 November 2003

Abstract

The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alkynes are discussed.
Keywords: α-Haloketones; annelated heterocycles; oxygen nucleophiles; nitrogen nucleophiles; sulfur nucleophiles; carbon nucleophiles α-Haloketones; annelated heterocycles; oxygen nucleophiles; nitrogen nucleophiles; sulfur nucleophiles; carbon nucleophiles
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Erian, A.W.; Sherif, S.M.; Gaber, H.M. The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis. Molecules 2003, 8, 793-865.

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