The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

doi:10.3390/81100793

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Molecules 2003, 8(11), 793-865; doi:10.3390/81100793

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The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

Ayman W. Erian^1,* , Sherif M. Sherif¹ and Hatem M. Gaber²

¹ Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt ² National Organization for Drug Control and Research (NODCAR), P.O. Box 29, Cairo, Egypt

* Author to whom correspondence should be addressed.

Received: 21 June 2003; in revised form: 15 August 2003 / Accepted: 18 August 2003 / Published: 15 November 2003

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Abstract: The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alkynes are discussed.

Keywords: α-Haloketones; annelated heterocycles; oxygen nucleophiles; nitrogen nucleophiles; sulfur nucleophiles; carbon nucleophiles

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MDPI and ACS Style

Erian, A.W.; Sherif, S.M.; Gaber, H.M. The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis. Molecules 2003, 8, 793-865.

AMA Style

Erian AW, Sherif SM, Gaber HM. The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis. Molecules. 2003; 8(11):793-865.

Chicago/Turabian Style

Erian, Ayman W.; Sherif, Sherif M.; Gaber, Hatem M. 2003. "The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis." Molecules 8, no. 11: 793-865.

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