Molecules 2002, 7(3), 353-362; doi:10.3390/70300353
Article

Synthesis of 2,3-Dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione

Department of Chemistry, University of the West Indies, Mona, Kingston 7, Jamaica
* Author to whom correspondence should be addressed.
Published: 31 March 2002
PDF Full-text Download PDF Full-Text [104 KB, uploaded 3 October 2008 08:19 CEST]
Abstract: Treatment of 5,6-dimethoxy-2-(methylphenylcarbamoyl)-benzofuran-3-carboxylic acid with PPA yielded 2,3-dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione. The analogous 2-[(5,6-dimethoxybenzofuran-2-carbonyl)methylamino]benzoic acid was resistant to cyclization, whereas 2-[(6-methoxybenzofuran-2-carbonyl)-amino]benzoic acid underwent cyclization to the corresponding 3,1-benzoxazin-4-one.
Keywords: PPA; cyclization; benzoxazinone; benzofuro-[2; 3-c]-[1]-benzazepin-6; 12-dione

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Jackson, Y.A.; Marriott, K.-S.C. Synthesis of 2,3-Dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione. Molecules 2002, 7, 353-362.

AMA Style

Jackson YA, Marriott K-SC. Synthesis of 2,3-Dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione. Molecules. 2002; 7(3):353-362.

Chicago/Turabian Style

Jackson, Yvette A.; Marriott, Karla-Sue C. 2002. "Synthesis of 2,3-Dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione." Molecules 7, no. 3: 353-362.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert