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Molecules 2002, 7(10), 751-755; doi:10.3390/71000751

Deprotection of Acetals and Ketals by Silica Sulfuric Acid and Wet SiO2

1, 2,*  and 3
1 Department of Chemistry, College of Science, Yazd University, Yazd, Iran 2 Department of Chemistry, College of Science, Bu-Ali Sina University, Hamadan 65174, P.O. Box 4135, Iran 3 Department of Chemistry, College of Science, Kashan University, Kashan 51167, Iran
* Author to whom correspondence should be addressed.
Received: 25 October 2001 / Revised: 13 October 2002 / Accepted: 14 October 2002 / Published: 31 October 2002
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Neat chlorosulfonic acid reacts with silica gel to give silica sulfuric acid in which sulfuric acid is immobilized on the surface of silica gel via covalent bonds. A combination of silica sulfuric acid and wet SiO2 was used as an effective deacetalizating agent for the conversion of acetals to their corresponding carbonyl derivatives under thermal conditions.
Keywords: Silica sulfuric acid; Deacetalization Silica sulfuric acid; Deacetalization
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Mirjalili, B.F.; Zolfigol, M.A.; Bamoniri, A. Deprotection of Acetals and Ketals by Silica Sulfuric Acid and Wet SiO2. Molecules 2002, 7, 751-755.

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