Silica Sulfuric Acid/ NaNO2 as a Novel Heterogeneous System for the Nitration of Phenols under Mild Conditions

doi:10.3390/71000734

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Molecules 2002, 7(10), 734-742; doi:10.3390/71000734

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Silica Sulfuric Acid/ NaNO₂ as a Novel Heterogeneous System for the Nitration of Phenols under Mild Conditions

Mohammad Ali Zolfigol* , Elahe Madrakian and Ezat Ghaemi

Department of Chemistry, College of Science, University of Bu-Ali Sina, Zip Code 65174, Post Box No. 4135, Hamadan, I.R. Iran

* Author to whom correspondence should be addressed.

Received: 2 October 2002; in revised form: 14 October 2002 / Accepted: 14 October 2002 / Published: 31 October 2002

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Abstract: Nitrophenols can be obtained in moderate to high yields via nitrosationoxidation of phenols with silica sulfuric acid, NaNO₂ and wet SiO₂ at room temperature. In situ generation of HNO₂ and a radical cation mechanism via the nitrous acid catalyzed (NAC) pathway appear to be applicable to phenol nitration using these reagents.

Keywords: Silica sulfuric acid; nitrosation-oxidation; nitration; nitrophenols

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MDPI and ACS Style

Zolfigol, M.A.; Madrakian, E.; Ghaemi, E. Silica Sulfuric Acid/ NaNO₂ as a Novel Heterogeneous System for the Nitration of Phenols under Mild Conditions. Molecules 2002, 7, 734-742.

AMA Style

Zolfigol MA, Madrakian E, Ghaemi E. Silica Sulfuric Acid/ NaNO₂ as a Novel Heterogeneous System for the Nitration of Phenols under Mild Conditions. Molecules. 2002; 7(10):734-742.

Chicago/Turabian Style

Zolfigol, Mohammad A.; Madrakian, Elahe; Ghaemi, Ezat. 2002. "Silica Sulfuric Acid/ NaNO₂ as a Novel Heterogeneous System for the Nitration of Phenols under Mild Conditions." Molecules 7, no. 10: 734-742.

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