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Molecules 2001, 6(6), 519-527; doi:10.3390/60600519
Article

Heteroaromatization with 4-Hydroxycoumarin Part II: Synthesis of Some New Pyrano[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines and Pyrimido[1,6-b]-[1,2,4]triazine Derivatives

1,* , 1, 2, 1 and 1
1 Department of Chemistry, Faculty of Science, Al- Azhar Univ. Nasr City, Cairo, Egypt 2 Department of Chemistry, Faculty of Science, Al- Azhar Univ. (Girls), Nasr City, Cairo, Egypt
* Author to whom correspondence should be addressed.
Received: 8 June 2000 / Revised: 16 September 2000 / Accepted: 15 February 2001 / Published: 31 May 2001
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Abstract

A variety of novel [1,2,4]triazolo[1,5-c]pyrimidine-13-ones (4a-f) and (5b-d) could be obtained via reaction of 9-amino-7-(4’-chlorophenyl)-8,9-dihydro-8-imino-6H,7H-[1]benzopyrano[3`,4`:5,6]pyrano[2,3-d]pyrimidine-6-one (3) with a variety of reagents. Pyrano[2,3-d]pyrimidine-6-ones 5a, 8a-c and pyrimido[1,6-b][1,2,4]-triazine-3,14-dione (6) were also prepared. The antimicrobial activity of some of the synthesized compounds was tested.
Keywords: Pyrano[3; 2-c][1]benzopyrans; Pyrano[2; 3-d]pyrimidines; [1; 2; 4]-triazolo- [1; 5-c]pyrimidines; Pyrimido[1; 6-b][1; 2; 4]triazine ; antimicrobial activities Pyrano[3; 2-c][1]benzopyrans; Pyrano[2; 3-d]pyrimidines; [1; 2; 4]-triazolo- [1; 5-c]pyrimidines; Pyrimido[1; 6-b][1; 2; 4]triazine; antimicrobial activities
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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El-Agrody, A.M.; Abd El-Latif, M.S.; El-Hady, N.A.; Fakery, A.H.; Bedair, A.H. Heteroaromatization with 4-Hydroxycoumarin Part II: Synthesis of Some New Pyrano[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines and Pyrimido[1,6-b]-[1,2,4]triazine Derivatives. Molecules 2001, 6, 519-527.

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