Molecules 2000, 5(6), 908-915; doi:10.3390/50600908
Article

Reduction and Preparation of a Phthalimide Derivative from a Furo-heliangolide

Received: 18 February 2000; Accepted: 20 June 2000 / Published: 27 June 2000
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Goyazensolide, a biologically active natural product classified as a furoheliangolide, was transformed in a phthalimide derivative that showed an enhanced biological activity against Tripanosoma cruzi. The complex natural product was also reduced with high stereoselectivity by hydrogen/Wilkinson’s catalyst; an epimer of this product was obtained in the reduction with hydrogen/Pd-C.
Keywords: Furo-heliangolides; Goyazensolide; Reduction; Phthalimide derivative; Wilkinson’s catalyst
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MDPI and ACS Style

Da Silva, G.V.J.; Heleno, V.C.G.; Constantino, M.G. Reduction and Preparation of a Phthalimide Derivative from a Furo-heliangolide. Molecules 2000, 5, 908-915.

AMA Style

Da Silva GVJ, Heleno VCG, Constantino MG. Reduction and Preparation of a Phthalimide Derivative from a Furo-heliangolide. Molecules. 2000; 5(6):908-915.

Chicago/Turabian Style

Da Silva, Gil V.J.; Heleno, Vladimir C.G.; Constantino, Mauricio G. 2000. "Reduction and Preparation of a Phthalimide Derivative from a Furo-heliangolide." Molecules 5, no. 6: 908-915.

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