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Molecules 1998, 3(7), 164-166; doi:10.3390/30700164
Article

Glutathione Peroxidase-like Activities of Oxygen-Containing Diselenides

Institut für Organische Chemie der Universität Basel, St. Johanns-Ring 19, CH – 4056 Basel, Switzerland
Received: 9 June 1998 / Accepted: 13 July 1998 / Published: 27 July 1998
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Abstract

Various diselenides 1 – 8 have been examined with respect to their glutathione peroxidase-like activities (GPx-activities) as an index of their antioxidant properties. The glutathione oxidase activities of these compounds have also been reviewed reflecting the pro-oxidant properties (GOx-activities) and could be used as an index of cell toxicity. Based on a qualitative structure-activity relationship some trends are suggested.
Keywords: Antioxidants; diselenides; glutatione oxidase; glutathione peroxidase; oxidative stress Antioxidants; diselenides; glutatione oxidase; glutathione peroxidase; oxidative stress
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Wirth, T. Glutathione Peroxidase-like Activities of Oxygen-Containing Diselenides. Molecules 1998, 3, 164-166.

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