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Molecules 1998, 3(4), 135-140;

Synthesis of 2-(6-Acetamidobenzothiazolethio)acetic Acid Esters as Photosynthesis Inhibitors

Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Mlynska dolina CH-2, SK-842 15 Bratislava, Slovakia
Author to whom correspondence should be addressed.
Received: 27 January 1998 / Accepted: 14 April 1998 / Published: 30 April 1998
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The synthesis and photosynthesis-inhibiting activity of 13 new 2-(6-acetamidobenzothiazolethio)acetic acid esters are reported. The new compounds were prepared by acetylation of 2-(alkoxycarbonylmethylthio)-6-aminobenzothiazoles with acetic anhydride. The structure of the compounds was verified by 1H NMR spectra. The compounds inhibit photosynthetic electron transfer in spinach chloroplasts. The structure - activity relation was studied. Lipophilicity was found to influence substantially photosynthetic electron transfer. View Full-Text
Keywords: Electron transfer inhibition; QSAR; lipophilicity Electron transfer inhibition; QSAR; lipophilicity

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Sidoova, E.; Kralova, K.; Loos, D. Synthesis of 2-(6-Acetamidobenzothiazolethio)acetic Acid Esters as Photosynthesis Inhibitors. Molecules 1998, 3, 135-140.

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