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Professor Sir Derek H. R. Barton (1918-1998)
Molecules 1998, 3(4), 135-140; doi:10.3390/30400135
Article

Synthesis of 2-(6-Acetamidobenzothiazolethio)acetic Acid Esters as Photosynthesis Inhibitors

* ,  and
Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Mlynska dolina CH-2, SK-842 15 Bratislava, Slovakia
* Author to whom correspondence should be addressed.
Received: 27 January 1998 / Accepted: 14 April 1998 / Published: 30 April 1998
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Abstract

The synthesis and photosynthesis-inhibiting activity of 13 new 2-(6-acetamidobenzothiazolethio)acetic acid esters are reported. The new compounds were prepared by acetylation of 2-(alkoxycarbonylmethylthio)-6-aminobenzothiazoles with acetic anhydride. The structure of the compounds was verified by 1H NMR spectra. The compounds inhibit photosynthetic electron transfer in spinach chloroplasts. The structure - activity relation was studied. Lipophilicity was found to influence substantially photosynthetic electron transfer.
Keywords: Electron transfer inhibition; QSAR; lipophilicity Electron transfer inhibition; QSAR; lipophilicity
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Sidoova, E.; Kralova, K.; Loos, D. Synthesis of 2-(6-Acetamidobenzothiazolethio)acetic Acid Esters as Photosynthesis Inhibitors. Molecules 1998, 3, 135-140.

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