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Molecules 2018, 23(9), 2333; https://doi.org/10.3390/molecules23092333

Chemical Constituents from Croton Species and Their Biological Activities

Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming 650224, China
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Received: 18 July 2018 / Revised: 7 September 2018 / Accepted: 10 September 2018 / Published: 12 September 2018
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Abstract

The genus Croton belongs to the Euphorbiaceae family, which comprises approximately 1300 species. Many Croton species have been used as folk medicines. This review focuses on the chemical constituents from Croton species and their relevant biological activities, covering the period from 2006 to 2018. A total of 399 new compounds, including 339 diterpenoids, were reported. Diterpenoids are characteristic components of the Croton species. These isolated compounds exhibited a broad spectrum of bioactivities, including cytotoxic, anti-inflammatory, antifungal, acetylcholinesterase inhibitory, and neurite outgrowth-promoting properties. The present review provides a significant clue for further research of the chemical constituents from the Croton species as potential medicines. View Full-Text
Keywords: Croton species; phytochemistry; biological activities; diterpenoids; cytotoxicity Croton species; phytochemistry; biological activities; diterpenoids; cytotoxicity
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Xu, W.-H.; Liu, W.-Y.; Liang, Q. Chemical Constituents from Croton Species and Their Biological Activities. Molecules 2018, 23, 2333.

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