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Molecules 2016, 21(8), 991; doi:10.3390/molecules21080991

Phenylethanoid Glycosides: Research Advances in Their Phytochemistry, Pharmacological Activity and Pharmacokinetics

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 28 June 2016 / Revised: 25 July 2016 / Accepted: 26 July 2016 / Published: 29 July 2016
View Full-Text   |   Download PDF [1087 KB, uploaded 3 August 2016]   |  


Phenylethanoid glycosides (PhGs) are widely distributed in traditional Chinese medicines as well as in other medicinal plants, and they were characterized by a phenethyl alcohol (C6-C2) moiety attached to a β-glucopyranose/β-allopyranose via a glycosidic bond. The outstanding activity of PhGs in diverse diseases proves their importance in medicinal chemistry research. This review summarizes new findings on PhGs over the past 10 years, concerning the new structures, their bioactivities, including neuroprotective, anti-inflammatory, antioxidant, antibacterial and antivirus, cytotoxic, immunomodulatory, and enzyme inhibitory effects, and pharmacokinetic properties. View Full-Text
Keywords: phenylethanoid glycosides; novel structures; bioactivity; pharmacokinetics phenylethanoid glycosides; novel structures; bioactivity; pharmacokinetics

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Xue, Z.; Yang, B. Phenylethanoid Glycosides: Research Advances in Their Phytochemistry, Pharmacological Activity and Pharmacokinetics. Molecules 2016, 21, 991.

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